The fate of substances in the environment is of increasing interest for authorities and manufacturers. We are able to perform biotic environmental fate studies starting on the level of screening tests for ready biodegradability up to higher tier studies with labeled and unlabeled substances in tailor-made test designs for the respective needs and regulatory requirements. Biotic transformation and degradation processes (aerobic and anaerobic) in different matrices and in different environmental compartments such as sewage treatment plants, surface waters, sediments and sea water are simulated and evaluated at standard laboratory temperatures as well as at environmentally realistic temperature conditions. The formation of metabolites and degradation products is investigated by specific analysis using state-of-the art LC-MS/MS, LC-HRMS, radio-HPLC and GC-MS/MS systems, even allowing metabolite identification. Abiotic transformation by hydrolysis, direct and indirect photolysis and photolysis on soil surface can be assessed, supported by excellent analytical quality regarding active compounds and metabolite confirmation / identification. The fate of substances and metabolites in organisms during uptake and depuration phases is evaluated by bioaccumulation studies in fish, earthworms or sediment worms like Lumbriculus. Soil leaching, partition coefficient and adsorption/desorption studies complete our broad portfolio.
Aerobic and Anaerobic Transformation in SoilOECD 307Aerobic and Anaerobic Transformation in Aquatic Sediment SystemsOECD 308Aerobic Mineralisation in Surface WaterOECD 309Simulation tests to assess the biodegradability of chemicals discharged in wastewaterOECD 314CAnaerobic Degradation in Manure
OECD 121 / EC C.19, OECD 106 / EC C.18, DIN/ISO/ASTM 18749
(HPLC method, Batch method)
Partition coefficient (log Po/w)
OECD 107 / EC A.8 , OECD 123, OECD 117 / EC A.8
(Flask method, slow stirring method, HPLC method)